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Purdue University has a distinguished reputation in nutrition and pharmacognosy research that dates back many generations. With the advent of the Dietary Supplement Health and Education Act of 1994, the use of botanicals has greatly increased, in some cases, without sufficient concern for safety of intake of various types. The Botanicals Center for Age Related Diseases, led by Purdue in collaboration with the University of Alabama-Birmingham, is one of six centers funded by the National Institutes of Health, Office of Dietary Supplements Core Center Projects (NCCAM) in the US.
Current Research
In addition to
several new projects funded by the Botanicals
Research Center for Age Related Diseases, several ongoing
research areas within the department include the influence
of soy isoflavones (phytoestrogens) on bone resorption in
postmenopausal women, polyphenols and cancer, grape phenols
and neuroprotection, and polyphenols and inflammation.
Contributors in the department
Engagement
The engagement portion of the NIH Botanicals Center for Age Related Diseases has been working collaboratively in support of the research projects and other activities and in developing educational programs for professionals. The engagement program has focused on developing Web sites and Internet-based programs on botanicals:
Learning
With the strength of the faculty interests, a graduate course "Women's Health and Nutrition," in which topics related to estrogen are discussed, is being revised under the new curriculum. The new two-credit course, "Polyphenolics (estrogens, phytoestrogen, catechins) and Health" will be co-taught by Connie Weaver, Dorothy Morre, and Dorothy Teegarden. In addition, a new one-credit course "Botanicals Metabolism" is being developed and will be coordinated by John Burgess.
National Reputation
Results of work with botanicals were recognized by the national and international press. The center director was selected to represent all botanicals centers for an NIH external review in 2003.
Publications in Last Five Years
Total number publications (26) or projects (14) with collaborators related to Botanicals for Age Related Diseases.
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Other F&N
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Other Purdue
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IUPUI
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Other
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Publications
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19
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65
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4
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35
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Research Projects
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29
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36
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7
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64
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Current Funding
- National Institutes of Health, Office of Dietary Supplements - center grant
- Purdue/UAB - 2 R01, 1 R03, 1 U54, 2 NCRR. shared instrument awards and several industry grants
- Institutional support to center (Purdue component) includes 2 graduate student stipends, and equipment matching funds
Potential Funding
- Pet food industry
- National Institute of Aging
Resources
- Purdue 1,020 sq. ft allocated for center use
- Six graduate students and two postdoctoral fellows are currently funded at Purdue by center grant
Collaborators
University of Alabama-Birmingham
- Steve Barnes, PhD (co-director); Victor Darley-Usmar, PhD; Helen Kim, PhD; and Dale Parks, PhD
- Rakesh Patel, PhD; Jeevan Prasain, PhD; Chao-Cheng Wang, PhD; Michael Wyss, PhD
Purdue University
- David Elmore, PhD, Physics; George Jackson, PhD, Physics; and George McCabe, PhD, Statistics
- D. James Morré, PhD, Medicinal Chemistry and Molecular Pharmacology; and David Waters, PhD, Veterinary Medicine
- Harvard University - Matthias Hediger, PhD, and Stephen Krasinski, PhD
- Indiana University School of Medicine: Howard Edenberg, PhD, and Munro Peacock, MD
- INSERM, Strasborg, FRA: Jean-Noel Freund, PhD
- MD Anderson Cancer Center: Sara Pelig, PhD
- National Institutes of Health: Julia Barsony, MD
- Rutgers University: Ming Fu, PhD; Jim Simon, PhD
- Tufts University: Richard Wood, PhD
- University of California, Riverside: Anthony Norman, PhD
- University of Illinois, Urbana-Champaign: Mary Ann Lila, PhD
- University of Medicine and Dentistry of New Jersey: Sylvia Christakos, PhD
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