F&N 436 - Fall 2000

Review for Final Exam

A. For each of the six Biochemical Assessment Labs Know:

1. Background Information covered in lecture and text on Nutrient or Physiological process

2. Assay Specifics - Chemistry

3. Calculation of Correct Unit values - given equation or standard curve

4. Interpretation of Result relative to range of normal values

B. Iron -

1. Review Blood collection method and which samples used for different assays

2. Review Spectrophotometric Method

- Lambert-Beer Law

3. Differentiating Iron-deficiency anemia from inflammation-induced anemia

A MCV of 130 fL indicates what regarding the erythrocyte?

A. Larger than normal

B. Smaller than normal

C. Could be the result of folate deficiency

D. Could be the result of Fe deficiency

E. A and C are both correct

Interpret the following hematocrit data obtained from an adult female. Duplicate hematocrit tubes: serum volume=3.7 cm, 3.8 cm; erythrocyte volume=2.2 cm, 2.3 cm; total volume= 5.9 cm, 5.8 cm.

A. 0.385, within the normal range

B. 0.365, below the normal range

C. 0.64, within the normal range

D. 0.64, below the normal range

E. 0.64, above the normal range

Normal Ranges:

Male - 0.40 - 0.54

Female - 0.37 - 0.47

Describe the Profile of three iron assessment results indicative of stage III iron-deficiency anemia.

C. Protein

1. Review ABCD methods to assess protein status

2. Review PEM

3. Review Markers of Protein Status

- Strengths & Weaknesses, Confounds

4. Immunocompetence

Which of the following is/are true?

A. The causes of primary PEM include AIDS, tuberculosis, & kidney/liver disease

B. Marasmus occurs as a result of somatic protein loss.

C. Edema is seen in kwashiorkor due to an increase in serum albumin.

D. Marasmus occurs as a result of visceral protein loss.

E. All are true

What does a total protein concentration of 4.0 g/dL in an adult indicate?



D. Kidney Function

1. Urine characteristics

2. Creatinine

3. Assessment of Kidney Function versus Somatic protein

The Creatinine-height index is used to assess which of the following?

A. Kidney function

B. Blood pressure regulation

C. Protein energy malnutrition

D. Protein intake requirements

E. Visceral protein status

What is the concern of using serum creatinine concentration as the sole assessment of kidney function?



F. Bone Health

1. Review Enzymes - saturation of substrates, etc.

2. Osteoporosis Facts -

3. Alkaline phosphatase Facts & Assay

- standard curve

4. Interpretation of ABCD data

Which of the following is not a risk factor for developing osteoporosis?

A. obesity

B. female

C. early menopause

D. low dietary calcium

E. family history

A hospitalized child presents with an serum alkaline phosphatase of 22 units. What else would you want to know?




G. Blood Lipids

1. Review Lipoproteins - type/processing

2. Atherosclerosis - Process/Risk factors

3. Measurement of Lipids in People - TG, total Cholesterol, HDL, calculate LDL - Inaccuracies

Which of the following lipoproteins contribute significant amounts of cholesterol to a total blood cholesterol analysis value on a blood sample collected from an individual that has fasted for 18 hours?

A. HDL cholesterol

B. LDL cholesterol

C. chylomicron cholesterol

D. all of the above

E. A and B only

True or false. The scavenger receptor for cholesterol is implicated in atherosclerosis because it will bind HDL particles and prevent them from clearing cholesterol from the circulation.



H. Blood Glucose

1. Review Disorders of glucose metabolism

- risk factors for diabetes

2. New (1997) classification & diagnostic criteria for diabetes

3. Assessment of long-term glucose control

4. Glucose Monitor

Which of the following serum glucose values would NOT be considered in the desireable range?

A. A casual glucose concentration of 200 mg/dL

B. A two hour blood glucose value of 120 mg/dL

C. A blood glucose measurement of 105 mg/dL

D. A fasting blood glucose value of 70 mg/dL



I. Counseling -

1. Questions #35-40 in Notes pp. 146-147

2.  Skills required, Patient acceptance factors, Examples of Approaches

3. Self-Management Model/Techniques & Stages of Change model - questions to probe, obstacles, etc.

4.  Comparison between Standard Medical Model & Self-Management Model

A counseling strategy that emphasizes that one can learn through practice to make better choices once they accept that its their choice to make is an example of:

A. person centered

B. behavior centered

C. rational-emotive therapy

D. reality centered